MITOMAP: Mitochondrial DNA Function Locations

Last Edited: Jun 18, 2024

Map Locus	Starting	Ending	Shorthand	Description	Reference

"MT-OHR57",57,57,"CR:OH57","H-strand origin","1""MT-HV2",57,372,"CR:HVS2","Hypervariable segment 2 [classic:73-340 ]","3""MT-OHR",110,441,"CR:OH","H-strand origins","4""MT-CSB1",213,235,"CR:CSB1","Conserved sequence block 1","2""MT-TFX",233,260,"CR:TFX","mtTF1 binding site","1""MT-TFY",276,303,"CR:TFY","mtTF1 binding site","1""MT-CSB2",299,315,"CR:CSB2","Conserved sequence block 2","3""MT-HPR",317,321,"CR:HPR","replication primer","2""MT-CSB3",346,363,"CR:CSB3","Conserved sequence block 3","2""MT-4H",371,379,"CR:mt4H","mt4 H-strand control element","1""MT-3H",384,391,"CR:mt3H","mt3 H-strand control element","1""MT-LSP",392,435,"CR:PL","L-strand promoter","5""MT-TFL",418,445,"CR:mtTF1","mtTF1 binding site","1""MT-HV3",438,574,"CR:HVS3","Hypervariable segment 3","2""MT-TFH",523,550,"CR:TFH","mtTF1 binding site","1""MT-HSP1",545,567,"CR:PH1","Major H-strand promoter","5""MT-TF",577,647,"F","tRNA phenylalanine","1""MT-HSP2",645,645,"PH2","Minor H-strand promoter","3""MT-RNR1",648,1601,"12S","12S ribosomal RNA","2""MT-MOTSc",1343,1393,"MOTS-C","MOTS-C (MRWQEMGYIFYPRKLR)","1""MT-TV",1602,1670,"V","tRNA valine","1""MT-RNR2",1671,3229,"16S","16S ribosomal RNA","2""MT-SHLP3",1707,1821,"SHLP3","Small HN-like peptide 3 (MLGYNFSSFPCGTISIAPGFNFYRLYFIWVNGLAKVVW)","1""MT-SHLP2",2092,2170,"SHLP2","Small HN-like peptide 2 (MGVKFFTLSTRFFPSVQRAVPLWTNS)","1""MT-SHLP4",2446,2524,"SHLP4","Small HN-like peptide 4 (MLEVMFLVNRRGKICRVPFTFFNLSL)","2""MT-SHLP1",2490,2561,"SHLP1","Small HN-like peptide 1 (MCHWAGGASNTGDARGDVFGKQAG)","1""MT-Hum",2634,2707,"Humanin","Humanin peptide (MAPRGFSCLLLLTSEIDLPVKRRA)","9""MT-SHLP5",2785,2858,"SHLP5","Small HN-like peptide 5 (MYCSEVGFCSEVAPTEIFNAGLVV)","2""MT-SHLP6",2992,3051,"SHLP6","Small HN-like peptide 6 (MLDQDIPMVQPLLKVRLFND)","2""MT-RNR3",3206,3229,"-","5S-like sequence","1""MT-TER",3229,3256,"-","Transcription terminator","4""MT-TL1",3230,3304,"L(UUA/G)","tRNA leucine 1","1""MT-NC1",3305,3306,"NC1","non-coding nucleotides","0""MT-ND1",3307,4262,"ND1","NADH Dehydrogenase subunit 1","3""MT-TI",4263,4331,"I","tRNA isoleucine","4""MT-TQ",4329,4400,"Q","tRNA glutamine","1""MT-NC2",4401,4401,"NC2","non-coding nucleotides","0""MT-TM",4402,4469,"M","tRNA methionine","1""MT-ND2",4470,5511,"ND2","NADH dehydrogenase subunit 2","2""MT-TW",5512,5579,"W","tRNA tryptophan","1""MT-NC3",5580,5586,"NC3","non-coding nucleotides","1""MT-TA",5587,5655,"A","tRNA alanine","1""MT-NC4",5656,5656,"NC4","non-coding nucleotides","1""MT-TN",5657,5729,"N","tRNA asparagine","1""MT-OLR",5721,5798,"OL","L-strand origin","5""MT-TC",5761,5826,"C","tRNA cysteine","1""MT-TY",5826,5891,"Y","tRNA tyrosine","1""MT-NC5",5892,5903,"NC5","non-coding nucleotides","0""MT-CO1",5904,7445,"COI","Cytochrome c oxidase subunit I","2""MT-TS1",7446,7514,"S(UCN)","tRNA serine 1","2""MT-NC6",7515,7517,"NC6","non-coding nucleotides","0""MT-TD",7518,7585,"D","tRNA aspartic acid","1""MT-CO2",7586,8269,"COII","Cytochrome c oxidase subunit II","1""MT-NC7",8270,8294,"NC7","non-coding nucleotides","1""MT-TK",8295,8364,"K","tRNA lysine","1""MT-NC8",8365,8365,"NC8","non-coding nucleotide","0""MT-ATP8",8366,8572,"ATPase8","ATP synthase F0 subunit 8","2""MT-ATP6",8527,9207,"ATPase6","ATP synthase F0 subunit 6","1""MT-CO3",9207,9990,"COIII","Cytochrome c oxidase subunit III","1""MT-TG",9991,10058,"G","tRNA glycine","1""MT-ND3",10059,10404,"ND3","NADH dehydrogenase subunit 3","2""MT-TR",10405,10469,"R","tRNA arginine","1""MT-ND4L",10470,10766,"ND4L","NADH dehydrogenase subunit 4L","2""MT-ND4",10760,12137,"ND4","NADH dehydrogenase subunit 4","2""MT-TH",12138,12206,"H","tRNA histidine","1""MT-TS2",12207,12265,"S(AGY)","tRNA serine2","1""MT-TL2",12266,12336,"L(CUN)","tRNA leucine2","1""MT-ND5",12337,14148,"ND5","NADH dehydrogenase subunit 5","2""MT-ND6",14149,14673,"ND6","NADH dehydrogenase subunit 6","2""MT-TE",14674,14742,"E","tRNA glutamic acid","1""MT-NC9",14743,14746,"NC9","non-coding nucleotides","0""MT-CYB",14747,15887,"Cytb","Cytochrome b","1""MT-TT",15888,15953,"T","tRNA threonine","1""MT-ATT",15925,499,"ATT","membrane attachment site","2""MT-NC10",15954,15955,"NC10","non-coding nucleotides","0""MT-TP",15956,16023,"P","tRNA proline","1""MT-CR",16024,576,"CR:Control Region","entire Control Region (including displacement loop)","4""MT-HV1",16024,16383,"CR:HVS1/HV1","Hypervariable segment 1 [classic:16024-16365]","3""MT-TAS2",16081,16138,"CR:TAS2","extended termination-associated sequence","2""MT-7SDNA",16106,191,"CR:7S-like","7S DNA","6""MT-TAS",16157,16172,"CR:TAS","termination-associated sequence","2""MT-5",16194,16208,"CR:mt5","control element","1""MT-3L",16499,16506,"CR:mt3L","L-strand control element","1"

Note: Locus names are the official designations delineated by the given nucleotide numbers. The map positions correspond to the nucleotide pair(np) numbers determined from the DNA sequence.

Notes: mtTF1=mitochondrial transcription factor, Y=either pyrimidine, N=any base.

H-strand replication origin positions have been identified at np 110, 147, 169, 191, 219, 310, 441.

L-strand promoter positions have been identified at np 407, 392-435.

H-strand promoter positions have been identified at np 559-561.

L-strand replication origin positions have been identified at np 5721-5781, 5761, 5799.